Route 143 in Iron County will be closed as Missouri Department of Transportation crews replace a culvert under the roadway.
This section of roadway is located 4.6 miles from Route 49.
Weather permitting, work will take place Wednesday, Aug. 12 from 8 a.m. to 1 p.m.
The work zone will be marked with signs. Motorists are urged to use extreme caution while traveling near the area.